منابع مشابه
Estrogens and atherosclerosis.
Numerous epidemiological as well as experimental studies have suggested that estradiol (E2) prevents atherosclerosis development. However two controlled prospective and randomized studies in women using hormone replacement therapy (HRT) did not confirm this beneficial effect. We then decided to use mouse models of atherosclerosis to define the possible mechanisms involved and the reasons for th...
متن کاملEstrogens, progestins, and atherosclerosis.
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملEstrogens, Progestins, and Atherosclerosis
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملEstrogens, Progestins, and Atherosclerosis
To the Editor: We feel compelled to comment on the Brief Review “Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?” by Koh and Sakuma.1 Specifically, although we agree with the suggestion that the effects of estrogen on the vasculature may depend on the extent and severity of existing atherosclerosis, we d...
متن کاملTelomeres and Estrogens: The Unholy Nexus in Pathogenesis of Atherosclerosis
Atherosclerosis (AS) is a complex inflammatory process and is categorized as a multifactorial disease involving the interplay of genetic and environmental factors. There are many factors which play role in predisposition and development of AS. In this review we have tried to address the basic pathophysiology of AS lesions and the role played by two important factors - telomeres and estrogens in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2004
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1500113